Description

(1S,3S,5S)-1,3,5-Tris(4-Nitrophenyl)Adamantane is a high-purity, stereochemically defined organic building block featuring a rigid adamantane core symmetrically substituted with three nitrophenyl groups. This compound matters for its unique three-dimensional structure and electronic properties, making it a valuable intermediate in advanced materials science and pharmaceutical research. It is needed by R&D chemists and process development scientists working on novel organic frameworks, such as Metal-Organic Frameworks (MOFs), covalent organic polymers, and as a potential precursor for high-performance materials.

Application

• Advanced Material Synthesis: A key precursor for constructing rigid, porous Metal-Organic Frameworks (MOFs) and Covalent Organic Frameworks (COFs) due to its trigonal symmetry and robust adamantane core.
• Pharmaceutical Intermediates: Serves as a sophisticated scaffold in medicinal chemistry for developing new molecular entities, leveraging its defined stereochemistry and potential for further functionalization.
• Ligand and Catalyst Development: Used in the design of novel ligands and organocatalysts where a bulky, shape-persistent architecture is required to influence reaction selectivity and efficiency.
• Polymer Science: Acts as a cross-linking agent or a core unit for synthesizing hyperbranched polymers and dendrimers with precise nanoscale dimensions.
• Energetic Materials Research: Investigated as a potential high-density, thermally stable component in specialized formulations, given its nitrated aromatic groups and stable cage structure.
• Organic Electronics: Explored as a building block for electron-transport materials or as a component in molecular devices due to the electron-withdrawing nitro groups.

Basic Information

Product Name	(1S,3S,5S)-1,3,5-Tris(4-Nitrophenyl)Adamantane
CAS No.	1298062-83-5
Molecular Formula	C30H27N3O6
Molecular Weight	525.55 g/mol
Synonyms	1,3,5-Tris(4-nitrophenyl)adamantane (all-S isomer); (1S,3S,5S)-Tris(4-nitrophenyl)adamantane; 1,3,5-Tris(p-nitrophenyl)adamantane; Adamantane-1,3,5-triyltris(4-nitrobenzene); Tris(4-nitrophenyl)adamantane; TNA; 1298062-83-5
EINECS	Contact for details

Quality Control

Our (1S,3S,5S)-1,3,5-Tris(4-Nitrophenyl)Adamantane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical identity, and impurity profile. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC, NMR, and chiral analysis, are validated to provide reliable specifications for advanced synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent any potential moisture uptake. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.