Description

1,4-Dioxa-9-Azadispiro[4.1.4.3]Tetradecane is a sophisticated spirocyclic compound featuring a unique heterocyclic architecture that combines ether and amine functionalities within a rigid, three-dimensional framework. This structural complexity makes it a highly valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry and organic synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Building Block: Used to introduce constrained spirocyclic motifs into new chemical entities to optimize potency, selectivity, and metabolic stability.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chelating ligands and organocatalysts due to its nitrogen and oxygen donor atoms.
• Agrochemical Research: Employed in the development of new active ingredients with unique modes of action.
• Material Science: Potential monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in synthetic organic chemistry and heterocyclic compound exploration.

Basic Information

Product Name	1,4-Dioxa-9-Azadispiro[4.1.4.3]Tetradecane
CAS No.	1297260-76-4
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	9-Aza-1,4-dioxadispiro[4.1.4.3]tetradecane; 1,4-Dioxa-9-azadispiro[4.1.4.3]tetradecane; Spirocyclic 1,4-dioxa-9-azatetradecane; Azaspirocyclic diether; CAS 1297260-76-4
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-9-Azadispiro[4.1.4.3]Tetradecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.