Description

1-(8-Nitro-3,4-Dihydro-2H-Quinolin-1-Yl)-Ethanone is a specialized nitro-substituted quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the life sciences sector who require high-purity building blocks for drug discovery, agrochemical synthesis, and material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the quinoline core for biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, including reduction of the nitro group or elaboration of the ketone moiety.
• Material Science: Potential intermediate for creating specialty chemicals, dyes, or photoactive materials due to its conjugated nitro-aromatic structure.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	1-(8-Nitro-3,4-Dihydro-2H-Quinolin-1-Yl)-Ethanone
CAS No.	1290608-24-0
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	1-(8-Nitro-1,2,3,4-tetrahydroquinolin-1-yl)ethanone; 8-Nitro-1-acetyl-1,2,3,4-tetrahydroquinoline; Ethanone, 1-(8-nitro-3,4-dihydro-2H-quinolin-1-yl)-; 1-Acetyl-8-nitro-1,2,3,4-tetrahydroquinoline; 8-Nitro-1-acetyl-1,2,3,4-tetrahydroquinoline; 1290608-24-0; 1-Acetyl-8-nitro-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 1-(8-Nitro-3,4-Dihydro-2H-Quinolin-1-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.