Description

(S)-3-(2,4-Dichloro-Benzyloxy)-Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring stereochemical control. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers engaged in the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-infective therapeutics.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	(S)-3-(2,4-Dichloro-Benzyloxy)-Pyrrolidine Hydrochloride
CAS No.	1289585-28-9
Molecular Formula	C11H14Cl3NO
Molecular Weight	306.59 g/mol
Synonyms	(S)-3-[(2,4-Dichlorophenyl)methoxy]pyrrolidine hydrochloride; (S)-3-(2,4-Dichlorobenzyloxy)pyrrolidine HCl; Pyrrolidine, 3-[(2,4-dichlorophenyl)methoxy]-, hydrochloride (1:1), (3S)-; (S)-3-(2,4-Dichloro-benzyloxy)-pyrrolidine HCl; (S)-3-(2,4-Dichlorobenzyloxy)pyrrolidine Hydrochloride; (S)-3-(2,4-Dichloro-Benzyloxy)-Pyrrolidine HCl; (S)-3-(2,4-Dichlorobenzyloxy)pyrrolidine monohydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-(2,4-Dichloro-Benzyloxy)-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation (NMR, MS) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.