Description

(2-Methyl-Benzyl)-(S)-Pyrrolidin-3-Yl-Amine Hydrochloride is a chiral amine hydrochloride salt, a high-purity advanced pharmaceutical intermediate. This compound is valued for its role as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, including potential candidates for neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of novel drug candidates.
• Neurological & Psychiatric Drug Development: Used in the preparation of compounds targeting receptors such as dopamine or serotonin receptors.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in stereoselective chemical reactions.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Pre-clinical & Clinical Trial Material: Supplied under GMP guidelines for the production of materials required for regulatory submissions and trials.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	(2-Methyl-Benzyl)-(S)-Pyrrolidin-3-Yl-Amine Hydrochloride
CAS No.	1289585-02-9
Molecular Formula	C13H20N2•HCl
Molecular Weight	240.77 g/mol
Synonyms	(S)-1-(2-Methylbenzyl)pyrrolidin-3-amine hydrochloride; (S)-3-Amino-1-(2-methylbenzyl)pyrrolidine hydrochloride; (S)-1-(2-Methylbenzyl)-3-pyrrolidinamine hydrochloride; (S)-N-(2-Methylbenzyl)pyrrolidin-3-amine HCl; (2-Methylbenzyl)-(S)-3-aminopyrrolidine hydrochloride; (S)-1-(o-Tolylmethyl)pyrrolidin-3-amine hydrochloride; (S)-1-(2-Methylphenyl)methyl-3-aminopyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Methyl-Benzyl)-(S)-Pyrrolidin-3-Yl-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and GMP production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.