Description

(R)-3-(2,5-Dichloro-Benzyloxy)-Pyrrolidine Hydrochloride CAS NO 1289584-87-7 is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its enantiomeric purity, which is critical for the development of active pharmaceutical ingredients (APIs) with specific stereochemical requirements. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to create complex molecules with defined chirality.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in enantioselective transformations.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical manufacturing.
• Biochemical Research: Applied in studies targeting specific enzymes or receptors where the (R)-enantiomer is biologically active.

Basic Information

Product Name	(R)-3-(2,5-Dichloro-Benzyloxy)-Pyrrolidine Hydrochloride
CAS No.	1289584-87-7
Molecular Formula	C11H14Cl3NO
Molecular Weight	306.59 g/mol
Synonyms	(R)-3-[(2,5-Dichlorophenyl)methoxy]pyrrolidine hydrochloride; (R)-3-(2,5-Dichlorobenzyloxy)pyrrolidine HCl; Pyrrolidine, 3-[(2,5-dichlorophenyl)methoxy]-, hydrochloride, (3R)-; (3R)-3-[(2,5-Dichlorobenzyl)oxy]pyrrolidine hydrochloride; (R)-3-(2,5-Dichloro-benzyloxy)-pyrrolidine HCl; 1289584-87-7; (R)-enantiomer of 3-(2,5-Dichlorobenzyloxy)pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-(2,5-Dichloro-Benzyloxy)-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.