Description

3-(2,5-Dichloro-Benzyloxymethyl)-Piperidine Hydrochloride CAS NO 1289387-86-5 is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperidine-based molecular structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the construction of complex molecules targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential APIs.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	3-(2,5-Dichloro-Benzyloxymethyl)-Piperidine Hydrochloride
CAS No.	1289387-86-5
Molecular Formula	C14H18Cl3NO
Molecular Weight	322.65 g/mol
Synonyms	3-[(2,5-Dichlorobenzyl)oxymethyl]piperidine hydrochloride; 3-((2,5-Dichlorobenzyloxy)methyl)piperidine HCl; Piperidine, 3-[(2,5-dichlorophenyl)methoxy]methyl]-, hydrochloride (1:1); 1289387-86-5; UNII-9K5F2V3L8F; 9K5F2V3L8F; 3-(2,5-Dichloro-benzyloxymethyl)-piperidine HCl
EINECS	Contact for details

Quality Control

Our 3-(2,5-Dichloro-Benzyloxymethyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.