Description

7-Piperidin-1-Yl-5-Azaspiro[2.4]Heptane Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern organic synthesis. This compound is valued for its unique spirocyclic and piperidine-containing structure, which is crucial for developing novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and process development of new therapeutic agents, particularly within central nervous system (CNS) and other specialty drug research programs.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry & Scale-Up: Serves as a key starting material or intermediate for optimizing synthetic routes during API development and pilot-scale production.
• Biochemical Tool Compound: Potential use in pharmacological research as a ligand or probe for studying specific biological pathways and protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring complex nitrogen-containing heterocycles.

Basic Information

Product Name	7-Piperidin-1-Yl-5-Azaspiro[2.4]Heptane Dihydrochloride
CAS No.	1286754-97-9
Molecular Formula	C14H27N3·2HCl
Molecular Weight	310.31 g/mol (free base: 237.39 g/mol)
Synonyms	5-Azaspiro[2.4]heptane, 7-(1-piperidinyl)-, dihydrochloride; 7-(Piperidin-1-yl)-5-azaspiro[2.4]heptane dihydrochloride; 1-(5-Azaspiro[2.4]heptan-7-yl)piperidine dihydrochloride; 7-Piperidin-1-yl-5-azaspiro[2.4]heptane dihydrochloride; 1286754-97-9; UNII-7H6Q6F2Q7R; 7H6Q6F2Q7R
EINECS	Contact for details

Quality Control

Our 7-Piperidin-1-Yl-5-Azaspiro[2.4]Heptane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.