Description

3-[4-(tert-Butoxycarbonylamino)Piperidine-1-Carbonyl]Benzoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting protease and kinase enzymes.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: The Boc-protected piperidine moiety is instrumental in creating peptide-like molecules with enhanced metabolic stability.
• Custom Synthesis Building Block: Employed in contract research and manufacturing (CRAM) for producing bespoke compounds for client-specific projects.
• Chemical Biology Probes: Useful for developing labeled compounds or affinity probes to study biological pathways and target engagement.

Basic Information

Product Name	3-[4-(tert-Butoxycarbonylamino)Piperidine-1-Carbonyl]Benzoic Acid
CAS No.	1286275-71-5
Molecular Formula	C18H24N2O5
Molecular Weight	348.40 g/mol
Synonyms	3-({4-[(tert-Butoxycarbonyl)amino]-1-piperidinyl}carbonyl)benzoic acid; 3-[(4-{[(tert-Butoxycarbonyl)amino]}piperidin-1-yl)carbonyl]benzoic acid; 3-(4-Boc-amino-piperidine-1-carbonyl)-benzoic acid; 3-(4-(Boc-amino)piperidine-1-carbonyl)benzoic acid; Benzoic acid, 3-[[4-[[(1,1-dimethylethoxy)carbonyl]amino]-1-piperidinyl]carbonyl]-; 1286275-71-5; Boc-4-Amino-piperidine-1-carboxylic acid (3-carboxy-phenyl)-amide
EINECS	Contact for details

Quality Control

Our production of 3-[4-(tert-Butoxycarbonylamino)Piperidine-1-Carbonyl]Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support development and cGMP-grade manufacturing to meet the exacting standards of the global pharmaceutical supply chain.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.