Description

4-(2-Fluoro-4-Nitrophenoxy)Tetrahydro-2H-Pyran is a specialized fluorinated nitrophenoxy derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a fluorine atom and a nitro group on the aromatic ring, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing new herbicides, pesticides, and plant growth regulators that require specific fluorinated aromatic motifs.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags, photoaffinity labels, or other molecular probes for biological target identification.
• Organic Synthesis Scaffold: Provides a versatile platform for further chemical modifications (e.g., reduction of nitro group, ether cleavage) to access a diverse library of derivatives for screening.

Basic Information

Product Name	4-(2-Fluoro-4-Nitrophenoxy)Tetrahydro-2H-Pyran
CAS No.	1286275-11-3
Molecular Formula	C11H12FNO4
Molecular Weight	241.22 g/mol
Synonyms	4-(2-Fluoro-4-nitrophenoxy)tetrahydro-2H-pyran; Tetrahydro-2H-pyran-4-yl 2-fluoro-4-nitrophenyl ether; 2-Fluoro-4-nitrophenyl tetrahydro-2H-pyran-4-yl ether; 4-(2-Fluoro-4-nitrophenoxy)oxane; 2H-Pyran, tetrahydro-4-[(2-fluoro-4-nitrophenyl)oxy]-; 4-(2-Fluoro-4-nitro-phenoxy)-tetrahydro-pyran
EINECS	Contact for details

Quality Control

Our production of 4-(2-Fluoro-4-Nitrophenoxy)Tetrahydro-2H-Pyran adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. As with many organic compounds, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.