Description

1-(Cyclobutylmethyl)Piperidin-4-Amine Dihydrochloride is a high-purity, pharmaceutically relevant amine salt used as a critical building block in organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new therapeutic agents.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile amine component in amide coupling, reductive amination, and other C-N bond-forming reactions.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Bioconjugation: Potential use in the modification of biomolecules and the synthesis of antibody-drug conjugates (ADCs).
• Ligand Synthesis: Useful for creating novel ligands for catalysis or receptor binding studies.

Basic Information

Product Name	1-(Cyclobutylmethyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1286274-85-8
Molecular Formula	C10H22Cl2N2
Molecular Weight	241.20 g/mol
Synonyms	4-Amino-1-(cyclobutylmethyl)piperidine dihydrochloride; 1-(Cyclobutylmethyl)-4-piperidinamine dihydrochloride; 4-Piperidinamine, 1-(cyclobutylmethyl)-, dihydrochloride; 1-Cyclobutylmethyl-piperidin-4-ylamine dihydrochloride; 1-(Cyclobutylmethyl)piperidin-4-amine hydrochloride (1:2); UNII-8J8W8Q7Z4N
EINECS	Contact for details

Quality Control

Our 1-(Cyclobutylmethyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.