Description

4-[(4-Fluoro-2-Nitrophenoxy)Methyl]Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Serves as a standard or starting material for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme inhibition or receptor binding.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	4-[(4-Fluoro-2-Nitrophenoxy)Methyl]Piperidine Hydrochloride
CAS No.	1286274-64-3
Molecular Formula	C12H14FN2O3·HCl
Molecular Weight	286.71 g/mol
Synonyms	4-[(4-Fluoro-2-nitrophenoxy)methyl]piperidine hydrochloride; 4-[(4-Fluoro-2-nitrophenoxy)methyl]piperidine HCl; Piperidine, 4-[(4-fluoro-2-nitrophenoxy)methyl]-, hydrochloride (1:1); 4-((4-Fluoro-2-nitrophenoxy)methyl)piperidine hydrochloride; 1286274-64-3; 4-(4-Fluoro-2-nitrophenoxymethyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[(4-Fluoro-2-Nitrophenoxy)Methyl]Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.