Description

1-(2-Fluoro-6-Nitrophenyl)Piperidin-4-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1286274-30-3. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D teams and manufacturers in the pharmaceutical and biotechnology sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its functionalized piperidine and aromatic nitro groups.
• API Synthesis: Serves as a precursor in multi-step synthetic routes for the production of target active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(2-Fluoro-6-Nitrophenyl)Piperidin-4-Amine Hydrochloride
CAS No.	1286274-30-3
Molecular Formula	C11H15FN3O2·HCl
Molecular Weight	261.71 (Free base) / 298.17 (Hydrochloride salt)
Synonyms	4-Amino-1-(2-fluoro-6-nitrophenyl)piperidine hydrochloride; 1-(2-Fluoro-6-nitrophenyl)-4-piperidinamine hydrochloride; 4-Piperidinamine, 1-(2-fluoro-6-nitrophenyl)-, hydrochloride; 1286274-30-3; 1-(2-Fluoro-6-nitrophenyl)piperidin-4-amine HCl
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-6-Nitrophenyl)Piperidin-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.