Description

(1R*,4R*)-N1-Isobutylcyclohexane-1,4-Diamine Dihydrochloride is a high-purity, stereochemically defined diamine hydrochloride salt. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry and diamine functionality. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring rigid, stereochemically controlled diamine scaffolds.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enabling enantioselective transformations in fine chemical manufacturing.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polyamides, polyurethanes, and epoxy curing agents with specific thermal and mechanical properties.
• Agrochemical Research: Employed as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Chelating Agent Precursor: Useful for synthesizing complexing agents for metal ion sequestration or in analytical chemistry applications.

Basic Information

Product Name	(1R*,4R*)-N1-Isobutylcyclohexane-1,4-Diamine Dihydrochloride
CAS No.	1286273-71-9
Molecular Formula	C10H24N2·2HCl
Molecular Weight	253.23 g/mol (free base: 180.31 g/mol)
Synonyms	(1R,4R)-N1-(2-Methylpropyl)cyclohexane-1,4-diamine dihydrochloride; (1R,4R)-1,4-Diamino-N-isobutylcyclohexane dihydrochloride; trans-N1-Isobutyl-1,4-cyclohexanediamine dihydrochloride; (1R,4R)-N-Isobutylcyclohexane-1,4-diamine dihydrochloride; Isobutyl-trans-1,4-diaminocyclohexane dihydrochloride; trans-1,4-Bis(aminocyclohexyl)butane dihydrochloride (related isomer); CAS 1286273-71-9
EINECS	Contact for details

Quality Control

Our (1R*,4R*)-N1-Isobutylcyclohexane-1,4-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.