Description

Methyl 2-(4-Aminopiperidine-1-Carbonyl)Benzoate Hydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its unique piperidine-benzoate hybrid structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• API Synthesis: Serves as a critical precursor in multi-step synthetic routes for the production of complex, high-value active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular framework.

Basic Information

Item	Details
Product Name	Methyl 2-(4-Aminopiperidine-1-Carbonyl)Benzoate Hydrochloride
CAS No.	1286265-06-2
Molecular Formula	C14H19N2O3·HCl
Molecular Weight	298.77 g/mol
Synonyms	Methyl 2-[(4-Aminopiperidin-1-yl)carbonyl]benzoate hydrochloride; 2-[(4-Aminopiperidine-1-carbonyl)]benzoic acid methyl ester hydrochloride; Methyl 2-(4-aminopiperidine-1-carboxamido)benzoate HCl; 1-(2-Methoxycarbonylbenzoyl)-4-aminopiperidine hydrochloride; Methyl o-(4-aminopiperidine-1-carboxamido)benzoate hydrochloride; Methyl 2-(4-aminopiperidine-1-carbonyl)benzoate HCl salt
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Aminopiperidine-1-Carbonyl)Benzoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.