Description

tert-Butyl 1-(cyclobutanecarbonyl)piperidin-4-ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected carbamate and a cyclobutanecarbonyl-piperidine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and other small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry.
• Protease Inhibitor Research: Used in the research and development of protease inhibitors, leveraging its specific molecular architecture.
• Kinase Inhibitor Scaffold: Serves as a core scaffold or building block for the development of potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and biological pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects under cGMP or non-GMP conditions.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and bio-active compound libraries.

Basic Information

Product Name	tert-Butyl 1-(Cyclobutanecarbonyl)Piperidin-4-Ylcarbamate
CAS No.	1286265-04-0
Molecular Formula	C15H26N2O3
Molecular Weight	282.38 g/mol
Synonyms	1-Boc-4-(cyclobutanecarbonylamino)piperidine; tert-Butyl N-[1-(cyclobutanecarbonyl)piperidin-4-yl]carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(cyclobutanecarbonyl)piperidine; 1-(Cyclobutanecarbonyl)-4-[(tert-butoxycarbonyl)amino]piperidine; 4-(Boc-amino)-1-cyclobutanecarbonylpiperidine; Piperidine-4-carboxylic acid, 1-cyclobutanoyl-4-[(tert-butoxycarbonyl)amino]-; BOC-Piperidine-4-yl-carbamic acid cyclobutylamide derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(cyclobutanecarbonyl)piperidin-4-ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply under more stringent quality agreements as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.