Description

1-(4-Bromobenzyl)Piperidin-4-Amine Dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, GPCRs, or kinase inhibitors.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile piperidine-amine scaffold and bromobenzyl moiety.
• Chemical Biology Probe Synthesis: Serves as a precursor for developing molecular probes and tool compounds for biological target validation and pathway analysis.
• Agrochemical Intermediate: Employed in the research and development of new active ingredients for crop protection products.
• Ligand Synthesis for Catalysis: Can be utilized to create novel chiral or achiral ligands for asymmetric synthesis and transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material or intermediate for custom synthesis projects and scale-up manufacturing under cGMP or ISO standards.

Basic Information

Product Name	1-(4-Bromobenzyl)Piperidin-4-Amine Dihydrochloride
CAS No.	1286264-50-3
Molecular Formula	C12H18BrCl2N2
Molecular Weight	350.10 g/mol
Synonyms	4-Amino-1-[(4-bromophenyl)methyl]piperidine dihydrochloride; 1-[(4-Bromophenyl)methyl]-4-piperidinamine dihydrochloride; 1-(4-Bromobenzyl)-4-aminopiperidine dihydrochloride; 4-Amino-1-(4-bromobenzyl)piperidine dihydrochloride; 1-(4-Bromobenzyl)piperidin-4-ylamine dihydrochloride; 4-Piperidinamine, 1-[(4-bromophenyl)methyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Bromobenzyl)Piperidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.