Description

2-[4-(tert-Butoxycarbonylamino)Piperidine-1-Carbonyl]Benzoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group and a carboxylic acid handle. This compound is critical for medicinal chemists as it enables the efficient synthesis and diversification of complex molecules, particularly in the development of protease inhibitors and other small-molecule therapeutics. It is primarily utilized by research institutions, CROs/CDMOs, and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the areas of oncology and antiviral research.
• Protease Inhibitor Synthesis: Serves as a core scaffold or precursor in the development of inhibitors targeting various proteases.
• Peptidomimetic Chemistry: Used to incorporate piperidine and benzoic acid motifs into peptide-like structures to enhance stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of tool compounds for target identification and validation studies.
• Custom Synthesis & Scale-Up: Supplied for custom synthesis projects, from milligram-scale research to kilogram-scale process development.
• Library Synthesis: Facilitates the generation of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	2-[4-(tert-Butoxycarbonylamino)Piperidine-1-Carbonyl]Benzoic Acid
CAS No.	1286263-62-4
Molecular Formula	C18H24N2O5
Molecular Weight	348.40 g/mol
Synonyms	2-({4-[(tert-Butoxycarbonyl)amino]-1-piperidinyl}carbonyl)benzoic acid; 2-[[4-[(2-Methylpropan-2-yl)oxycarbonylamino]piperidine-1-carbonyl]]benzoic acid; 2-(4-Boc-amino-piperidine-1-carbonyl)-benzoic acid; 2-(4-((tert-Butoxycarbonyl)amino)piperidine-1-carboxamido)benzoic acid; 1-(2-Carboxybenzoyl)-4-[(tert-butoxycarbonyl)amino]piperidine; Boc-4-Amino-piperidine-1-carboxylic acid 2-carboxy-phenyl ester; 1286263-62-4
EINECS	Contact for details

Quality Control

Our 2-[4-(tert-Butoxycarbonylamino)Piperidine-1-Carbonyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures a reliable supply of high-purity intermediates for critical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.