Description

4-[(Piperidine-4-Ylamino)Methyl]Benzonitrile Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1286263-50-0. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Development: A potential building block for compounds targeting specific enzymatic pathways.
• Kinase Inhibitor Synthesis: Employed in the creation of novel kinase inhibitors for oncology research.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	4-[(Piperidine-4-Ylamino)Methyl]Benzonitrile Dihydrochloride
CAS No.	1286263-50-0
Molecular Formula	C14H20Cl2N3
Molecular Weight	301.24 g/mol
Synonyms	4-[(4-Aminopiperidin-1-yl)methyl]benzonitrile dihydrochloride; 4-((4-Aminopiperidin-1-yl)methyl)benzonitrile dihydrochloride; 1-(4-Cyanobenzyl)piperidin-4-amine dihydrochloride; 4-[(Piperidin-4-ylamino)methyl]benzonitrile dihydrochloride; 4-(Piperidin-4-ylaminomethyl)benzonitrile dihydrochloride; Benzonitrile, 4-[(4-aminopiperidino)methyl]-, dihydrochloride; 1286263-50-0
EINECS	Contact for details

Quality Control

Our 4-[(Piperidine-4-Ylamino)Methyl]Benzonitrile Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.