Description

(S)-n-[(2-Fluorophenyl)Methyl]Piperidin-3-Amine Dihydrochloride is a high-purity chiral amine derivative, specifically the dihydrochloride salt of a fluorinated piperidine compound. This product is a critical pharmaceutical intermediate and research chemical valued for its defined stereochemistry and structural motif, which is essential for modulating biological activity and pharmacokinetic properties. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chiral Ligand/Synthon: Used in asymmetric synthesis to induce stereoselectivity in the formation of new carbon-carbon or carbon-heteroatom bonds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Intermediate in the research and production of advanced crop protection agents and pesticides.
• Biochemical Tool Compound: Used in pharmacological studies to investigate specific receptor interactions and enzyme inhibition.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(S)-n-[(2-Fluorophenyl)Methyl]Piperidin-3-Amine Dihydrochloride
CAS No.	1286209-37-7
Molecular Formula	C12H18Cl2FN2
Molecular Weight	277.19 g/mol
Synonyms	(S)-1-[(2-Fluorophenyl)methyl]piperidin-3-amine dihydrochloride; (S)-3-Amino-1-(2-fluorobenzyl)piperidine dihydrochloride; (S)-1-(2-Fluorobenzyl)piperidin-3-amine dihydrochloride; (3S)-1-[(2-Fluorophenyl)methyl]-3-piperidinamine dihydrochloride; (S)-N-[(2-Fluorophenyl)methyl]piperidin-3-amine dihydrochloride; (S)-1-(2-Fluorobenzyl)-3-aminopiperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-n-[(2-Fluorophenyl)Methyl]Piperidin-3-Amine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including Chiral HPLC for enantiomeric excess verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.