Description

(S)-1-(Cyclopropylmethyl)Pyrrolidin-3-Amine Dihydrochloride CAS NO 1286208-85-2 is a high-purity, chiral amine salt of significant importance in advanced pharmaceutical research and development. Its core value lies in its utility as a critical chiral building block and intermediate for synthesizing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This compound is essential for medicinal chemists, process R&D scientists, and manufacturers in the pharmaceutical and biotechnology industries who require high-quality, well-characterized intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in neuroscience and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Development: Serves as a critical precursor in the development and optimization of new APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its defined stereochemistry and functional groups.
• Process Chemistry & Scale-Up: Employed in route scouting, process development, and the manufacture of clinical trial materials.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in enantioselective synthesis.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	(S)-1-(Cyclopropylmethyl)Pyrrolidin-3-Amine Dihydrochloride
CAS No.	1286208-85-2
Molecular Formula	C9H18N2 • 2HCl
Molecular Weight	239.18 g/mol
Synonyms	(S)-1-(Cyclopropylmethyl)-3-aminopyrrolidine dihydrochloride; (3S)-1-(Cyclopropylmethyl)-3-pyrrolidinamine dihydrochloride; (S)-1-(Cyclopropylmethyl)pyrrolidin-3-amine hydrochloride (1:2); (S)-3-Amino-1-(cyclopropylmethyl)pyrrolidine dihydrochloride; (S)-1-Cyclopropylmethyl-3-aminopyrrolidine dihydrochloride; (S)-CPMA dihydrochloride; (S)-1-CPM-Pyrrolidin-3-amine 2HCl
EINECS	Contact for details

Quality Control

Our (S)-1-(Cyclopropylmethyl)Pyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, chiral integrity, and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment aligns with standards expected for pharmaceutical intermediates, supporting our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.