Description

(R)-n-(Pyridin-2-Ylmethyl)Piperidin-3-Amine Trihydrochloride CAS NO 1286208-76-1 is a high-purity chiral amine derivative, specifically the trihydrochloride salt of a piperidine-pyridine hybrid compound. This material serves as a critical pharmaceutical intermediate and building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and other therapeutic targets.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries and exploring structure-activity relationships (SAR).
• Ligand Synthesis: Employed in the development of novel ligands for receptors and enzymes, particularly in neuroscience research.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective chemical transformations.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological pathways and protein function.
• Agrochemical Development: Potential use as an intermediate in the synthesis of advanced crop protection agents.

Basic Information

Product Name	(R)-n-(Pyridin-2-Ylmethyl)Piperidin-3-Amine Trihydrochloride
CAS No.	1286208-76-1
Molecular Formula	C12H20N3•3HCl
Molecular Weight	326.68 g/mol (free base: 206.31 g/mol)
Synonyms	(R)-N-[(Pyridin-2-yl)methyl]piperidin-3-amine trihydrochloride; (R)-3-Amino-1-[(pyridin-2-yl)methyl]piperidine trihydrochloride; (R)-1-((Pyridin-2-yl)methyl)piperidin-3-amine trihydrochloride; (R)-N-(Pyridin-2-ylmethyl)piperidin-3-amine hydrochloride (1:3); (3R)-1-(Pyridin-2-ylmethyl)piperidin-3-amine trihydrochloride; (R)-1-(Pyridin-2-ylmethyl)piperidin-3-amine trihydrochloride; (R)-1-(2-Pyridylmethyl)-3-aminopiperidine trihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-n-(Pyridin-2-Ylmethyl)Piperidin-3-Amine Trihydrochloride is manufactured under strict quality control protocols to ensure high chemical and chiral purity suitable for research and development applications. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.