Description

(R)-1-(4-Nitrobenzyl)Pyrrolidin-3-Aminedihydrochloride is a high-purity chiral amine derivative, specifically the dihydrochloride salt of a pyrrolidine-based compound. This product is valued for its role as a critical pharmaceutical intermediate and building block in advanced organic synthesis. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and other specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective chemical reactions to create enantiomerically pure compounds.
• Chemical Research: Serves as a valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.
• Ligand and Catalyst Development: Potential precursor for creating novel ligands and catalysts used in transition metal-catalyzed reactions.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-1-(4-Nitrobenzyl)Pyrrolidin-3-Aminedihydrochloride
CAS No.	1286208-71-6
Molecular Formula	C11H16N3O2 · 2HCl
Molecular Weight	307.19 g/mol (free base: 218.27 g/mol)
Synonyms	(R)-1-(4-Nitrobenzyl)-3-aminopyrrolidine dihydrochloride; (3R)-1-[(4-Nitrophenyl)methyl]-3-pyrrolidinamine dihydrochloride; (R)-1-(4-Nitrobenzyl)pyrrolidin-3-amine dihydrochloride; (R)-1-(p-Nitrobenzyl)-3-aminopyrrolidine dihydrochloride; (R)-3-Amino-1-(4-nitrobenzyl)pyrrolidine dihydrochloride; (R)-1-(4-Nitrobenzyl)-3-pyrrolidinamine dihydrochloride; (R)-1-(4-Nitrobenzyl)-3-aminopyrrolidine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Nitrobenzyl)Pyrrolidin-3-Aminedihydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.