Description

(S)-1-(4-Bromobenzyl)Pyrrolidin-3-Aminedihydrochloride is a high-purity chiral amine derivative, specifically a pyrrolidine-based compound with a 4-bromobenzyl substituent. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research, valued for its defined stereochemistry and functional group versatility. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries and exploring structure-activity relationships (SAR).
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis and metal complexation.
• Bioconjugation: The amine functionality allows for conjugation to biomolecules, peptides, or fluorescent probes for biochemical studies.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study biological pathways and enzyme function.
• Process Chemistry Development: Employed in route scouting and optimization for scalable API manufacturing processes.

Basic Information

Product Name	(S)-1-(4-Bromobenzyl)Pyrrolidin-3-Aminedihydrochloride
CAS No.	1286208-58-9
Molecular Formula	C11H16BrN2·2HCl
Molecular Weight	352.09 g/mol (as dihydrochloride salt)
Synonyms	(S)-1-[(4-Bromophenyl)methyl]-3-pyrrolidinamine dihydrochloride; (3S)-1-[(4-Bromophenyl)methyl]-3-pyrrolidinamine dihydrochloride; (S)-1-(4-Bromobenzyl)-3-aminopyrrolidine dihydrochloride; (S)-3-Amino-1-(4-bromobenzyl)pyrrolidine dihydrochloride; (S)-1-(4-Bromobenzyl)pyrrolidin-3-amine hydrochloride (1:2); (S)-1-(p-Bromobenzyl)-3-aminopyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(4-Bromobenzyl)Pyrrolidin-3-Aminedihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, chiral purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical research and chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.