Description

(S)-n-(Pyridin-3-Ylmethyl)Piperidin-3-Amine Trihydrochloride is a high-purity chiral amine building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for creating novel active pharmaceutical ingredients (APIs) with specific stereochemistry. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Serves as a precursor for the development of chiral ligands and catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Process Chemistry Development: Used for scaling up synthetic routes and developing robust, GMP-compliant manufacturing processes for advanced intermediates.
• Academic Research: A valuable reagent for universities and research institutes conducting studies in organic synthesis and pharmacology.

Basic Information

Product Name	(S)-n-(Pyridin-3-Ylmethyl)Piperidin-3-Amine Trihydrochloride
CAS No.	1286208-56-7
Molecular Formula	C12H22Cl3N3
Molecular Weight	314.68 g/mol
Synonyms	(S)-N-((Pyridin-3-yl)methyl)piperidin-3-amine trihydrochloride; (S)-3-Amino-N-(pyridin-3-ylmethyl)piperidine trihydrochloride; (S)-N-(3-Pyridylmethyl)-3-piperidinamine trihydrochloride; (S)-1-[(Pyridin-3-yl)methyl]piperidin-3-amine trihydrochloride; (3S)-N-(Pyridin-3-ylmethyl)piperidin-3-amine trihydrochloride; (S)-Norchlorpheniramine impurity; (S)-N-(3-Picolyl)-3-aminopiperidine trihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-n-(Pyridin-3-Ylmethyl)Piperidin-3-Amine Trihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.