Description

(S)-1-(2-Nitrophenyl)Pyrrolidin-3-Aminehydrochloride CAS NO 1286207-80-4 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with specific biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the specific stereochemistry can influence biological efficacy and environmental safety.
• Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study biological pathways and protein function.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in synthetic methodology and medicinal chemistry projects.
• Custom Synthesis Building Block: Supplied for bespoke synthesis services to create specialized compounds for client-specific applications.

Basic Information

Product Name	(S)-1-(2-Nitrophenyl)Pyrrolidin-3-Aminehydrochloride
CAS No.	1286207-80-4
Molecular Formula	C10H14N3O2•HCl
Molecular Weight	253.70 g/mol
Synonyms	(S)-1-(2-Nitrophenyl)-3-aminopyrrolidine hydrochloride; (3S)-1-(2-Nitrophenyl)pyrrolidin-3-amine hydrochloride; (S)-3-Amino-1-(2-nitrophenyl)pyrrolidine HCl; 1-(2-Nitrophenyl)-L-prolinamine hydrochloride; (S)-1-(2-Nitro-phenyl)-pyrrolidin-3-ylamine hydrochloride; (S)-1-(o-Nitrophenyl)-3-aminopyrrolidine hydrochloride; (S)-N1-(2-Nitrophenyl)pyrrolidine-3-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(2-Nitrophenyl)Pyrrolidin-3-Aminehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥98.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.