Description

(S)-3-(2-Nitrophenoxy)Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective synthesis to construct complex molecules with high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of more complex, proprietary compounds under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	(S)-3-(2-Nitrophenoxy)Pyrrolidine Hydrochloride
CAS No.	1286207-04-2
Molecular Formula	C10H13N2O3·HCl
Molecular Weight	244.68 g/mol (Free base: 208.22 g/mol)
Synonyms	(S)-3-(2-Nitrophenoxy)pyrrolidine HCl; (S)-3-(o-Nitrophenoxy)pyrrolidine hydrochloride; (S)-2-Nitrophenyl pyrrolidin-3-yl ether hydrochloride; Pyrrolidine, 3-[(2-nitrophenyl)oxy]-, hydrochloride, (3S)-; (3S)-3-(2-Nitrophenoxy)pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (S)-3-(2-Nitrophenoxy)Pyrrolidine Hydrochloride is manufactured and tested under strict quality management systems. We ensure compliance with high-purity standards suitable for pharmaceutical research and development. Comprehensive analytical testing, including chiral purity verification by HPLC, is performed. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.