Description

3-Fluorocyclobutanamine Hydrochloride is a high-purity organic building block featuring a fluorinated cyclobutane scaffold. This compound is valued for its role in medicinal chemistry and drug discovery, where its unique structure is leveraged to modulate the physicochemical and metabolic properties of target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets. The CAS number for this material is 1284245-36-8.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for CNS-targeted drugs.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to introduce fluorine atoms, which can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Serves as a building block in the synthesis of novel herbicides, fungicides, and pesticides with improved efficacy.
• Chemical Biology: Employed as a probe or linker in the synthesis of molecules for studying biological pathways and protein interactions.
• Material Science: Potential precursor for advanced polymers or liquid crystals where the fluorinated cyclobutane unit imparts specific thermal or optical properties.

Basic Information

Product Name	3-Fluorocyclobutanamine Hydrochloride
CAS No.	1284245-36-8
Molecular Formula	C4H9FN • HCl
Molecular Weight	139.58 g/mol (free base)
Synonyms	3-Fluorocyclobutan-1-amine hydrochloride; 1-Amino-3-fluorocyclobutane hydrochloride; 3-Fluorocyclobutylamine hydrochloride; 3-Fluoro-1-aminocyclobutane HCl; 3-F-CBA HCl; FCBA HCl; (3-Fluorocyclobutyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Fluorocyclobutanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and MS analyses. Our quality commitment aligns with the standards required for research and development applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.