Description

4-Biphenyl-[1,3]Dioxol-5-Yl-Carboxylic Acid is a specialized aromatic carboxylic acid derivative featuring a biphenyl core fused with a dioxolane ring system. This unique molecular architecture makes it a valuable high-purity building block for advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and functional intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its complex aromatic structure.
• Ligand and Catalyst Development: The carboxylic acid and dioxolane functional groups make it suitable for designing chelating ligands for metal catalysis or organocatalysts.
• Material Science & Organic Electronics: Acts as a monomer or dopant for constructing advanced polymers, liquid crystals, or charge-transport materials.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes and tags for studying biological systems and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring this precise chemical scaffold.

Basic Information

Item	Details
Product Name	4-Biphenyl-[1,3]Dioxol-5-Yl-Carboxylic Acid
CAS No.	1284227-22-0
Molecular Formula	C16H12O4
Molecular Weight	268.26 g/mol
Synonyms	5-(Biphenyl-4-yl)-1,3-dioxole-4-carboxylic acid; 4-Biphenylyl-1,3-dioxol-5-carboxylic acid; [1,3]Dioxolo[4,5-c]biphenyl-5-carboxylic acid; 5-(4-Phenylphenyl)-1,3-benzodioxole-4-carboxylic acid; 4-Carboxy-5-(4-phenylphenyl)-1,3-benzodioxole; 4-Biphenylyl-[1,3]dioxol-5-yl-carboxylic acid
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for this intermediate typically meets a purity specification of ≥97% (by HPLC), suitable for research and development applications. For process-scale or cGMP applications, higher purity grades (≥98% or ≥99%) can be supplied. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.