Description

3-Acetyl-6-Chloro-4-(4-Methylphenyl)Quinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic quinoline structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines. It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical suppliers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, especially in oncology and anti-infective research.
• Organic Synthesis Building Block: Used in research laboratories for constructing novel quinoline-based heterocyclic compounds.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents and pesticides.
• Material Science: Investigated for use in the development of organic electronic materials and functional dyes due to its conjugated system.
• Biochemical Research: Employed in studies targeting specific enzymes or biological pathways where the quinoline scaffold is active.

Basic Information

Product Name	3-Acetyl-6-Chloro-4-(4-Methylphenyl)Quinolin-2(1H)-One
CAS No.	1283108-80-4
Molecular Formula	C18H14ClNO2
Molecular Weight	311.76 g/mol
Synonyms	3-Acetyl-6-chloro-4-(p-tolyl)-1H-quinolin-2-one; 6-Chloro-3-acetyl-4-(4-methylphenyl)-2(1H)-quinolinone; 2(1H)-Quinolinone, 3-acetyl-6-chloro-4-(4-methylphenyl)-; 3-Acetyl-6-chloro-4-(4-methylphenyl)-1,2-dihydroquinolin-2-one; 3-Acetyl-6-chloro-4-(p-methylphenyl)-2(1H)-quinolinone
EINECS	Contact for details

Quality Control

Our 3-Acetyl-6-Chloro-4-(4-Methylphenyl)Quinolin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.