Description

3-Acetyl-6-Chloro-4-(4-Chlorophenyl)Quinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1283108-77-9. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where consistent quality and structural integrity are paramount. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic APIs, particularly in oncology and anti-infective research.
• Agrochemical Research: Serves as a foundational scaffold for developing new herbicides and fungicides with targeted modes of action.
• Chemical Synthesis: Used in organic chemistry research for constructing quinoline-based molecular libraries for drug discovery.
• Material Science: Investigated as a potential monomer or additive for creating specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	3-Acetyl-6-Chloro-4-(4-Chlorophenyl)Quinolin-2(1H)-One
CAS No.	1283108-77-9
Molecular Formula	C17H11Cl2NO2
Molecular Weight	332.18 g/mol
Synonyms	3-Acetyl-6-chloro-4-(4-chlorophenyl)-1,2-dihydroquinolin-2-one; 3-Acetyl-6-chloro-4-(4-chlorophenyl)-2(1H)-quinolinone; 6-Chloro-4-(4-chlorophenyl)-3-acetyl-1H-quinolin-2-one; 4-(4-Chlorophenyl)-6-chloro-3-acetyl-1,2-dihydro-2-quinolinone; 3-Acetyl-6-chloro-4-(p-chlorophenyl)-2(1H)-quinolinone; 1283108-77-9; Quinolin-2(1H)-one, 3-acetyl-6-chloro-4-(4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our production of 3-Acetyl-6-Chloro-4-(4-Chlorophenyl)Quinolin-2(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to in-house specifications aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.