Description

4-Amino-3-((tert-Butoxycarbonyl)Amino)Benzoic Acid is a specialized, high-purity chemical building block featuring both a carboxylic acid and a Boc-protected amine group on an aromatic ring. This compound is critically important for its role as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptors or enzymes.
• Peptide Mimetics & Conjugates: Used to incorporate aromatic, functionalized amino acid analogs into peptide chains to enhance stability, bioavailability, or binding affinity.
• Proteolysis-Targeting Chimeras (PROTACs) & Molecular Glues: Serves as a versatile linker or component in the design of targeted protein degradation therapeutics.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, or plant growth regulators.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialized polymers, dendrimers, or metal-organic frameworks (MOFs).
• Bioconjugation & Labeling: The carboxylic acid group enables coupling to biomolecules (proteins, antibodies) for diagnostic or therapeutic applications.
• Chemical Biology Probes: Used to develop tool compounds for studying biological pathways and protein function.

Basic Information

Product Name	4-Amino-3-((tert-Butoxycarbonyl)Amino)Benzoic Acid
CAS No.	1282523-83-4
Molecular Formula	C₁₂H₁₆N₂O₄
Molecular Weight	252.27 g/mol
Synonyms	3-((tert-Butoxycarbonyl)amino)-4-aminobenzoic acid; 4-Amino-3-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid; 4-Amino-3-(Boc-amino)benzoic acid; Boc-3,4-diaminobenzoic acid (Boc-DABA); 3-(Boc-amino)-4-aminobenzoic acid; Benzoic acid, 4-amino-3-[[(1,1-dimethylethoxy)carbonyl]amino]-; 1282523-83-4
EINECS	Contact for details

Quality Control

Our 4-Amino-3-((tert-Butoxycarbonyl)Amino)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.