Description

(S)-2-Hydroxy-2’-[(R)-Hydroxy(o-Tolyl)Methyl]-[1,1’-Binaphthalene] is a sophisticated chiral binaphthyl derivative, serving as a high-value ligand and building block in asymmetric synthesis. Its precise stereochemistry makes it a critical component for inducing enantioselectivity in catalytic reactions, directly impacting the efficiency and purity of advanced chemical manufacturing. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty fine chemical sectors who require reliable, high-purity chiral auxiliaries.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation.
• Key intermediate in the synthesis of enantiomerically pure pharmaceuticals and active pharmaceutical ingredients (APIs).
• Building block for constructing complex molecular architectures in advanced material science and supramolecular chemistry.
• Use in the development and screening of novel catalysts for industrial-scale enantioselective processes.
• Precursor for chiral stationary phases used in high-performance liquid chromatography (HPLC) for enantiomer separation.
• Research and development of novel agrochemicals with specific stereochemical requirements for enhanced activity.

Basic Information

Product Name	(S)-2-Hydroxy-2’-[(R)-Hydroxy(o-Tolyl)Methyl]-[1,1’-Binaphthalene]
CAS No.	1281985-77-0
Molecular Formula	C28H22O2
Molecular Weight	390.48 g/mol
Synonyms	(S)-2-Hydroxy-2'-[(R)-Hydroxy(o-tolyl)methyl]-1,1'-binaphthalene; (S)-2-Hydroxy-2'-[(R)-1-(2-Methylphenyl)-1-hydroxyethyl]-1,1'-binaphthyl; (S)-2'-[(R)-Hydroxy(o-tolyl)methyl]-2-hydroxy-1,1'-binaphthalene; (S)-2-Hydroxy-2'-[(R)-Hydroxy(2-methylphenyl)methyl]-1,1'-binaphthalene; Chiral Binaphthol Derivative; BINOL Derivative Ligand; (S,R)-NOBIN-Tolyl Derivative
EINECS	Contact for details

Quality Control

Every batch of our (S)-2-Hydroxy-2’-[(R)-Hydroxy(o-Tolyl)Methyl]-[1,1’-Binaphthalene] is subjected to rigorous analytical testing to ensure it meets the stringent purity and stereochemical integrity required for advanced synthetic applications. We employ state-of-the-art techniques including chiral HPLC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and full analytical data is provided with each shipment to guarantee traceability and compliance with your research or cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.