Description

2,7-Diazaspiro[4.5]Decane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester, (Hydrochloride)(1:1) is a high-purity, protected spirocyclic amine building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling medicinal chemists to explore novel therapeutic candidates. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for drug discovery programs targeting central nervous system (CNS) disorders and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization stages for constructing complex spirocyclic scaffolds with potential biological activity.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of protease inhibitors.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme function and biological pathways.
• Library Synthesis: A valuable reagent for generating diverse compound libraries in high-throughput screening campaigns.
• Process Chemistry: Used in route scouting and scale-up synthesis for preclinical and clinical-stage compounds.

Basic Information

Product Name	2,7-Diazaspiro[4.5]Decane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester, (Hydrochloride)(1:1)
CAS No.	1279856-08-4
Molecular Formula	C13H25N2O2 • HCl
Molecular Weight	276.81 g/mol (Free base: 241.35 g/mol)
Synonyms	tert-Butyl 2,7-diazaspiro[4.5]decane-7-carboxylate hydrochloride; 7-Boc-2,7-diazaspiro[4.5]decane hydrochloride; 2,7-Diazaspiro[4.5]decane-7-carboxylic acid tert-butyl ester hydrochloride; 7-(tert-Butoxycarbonyl)-2,7-diazaspiro[4.5]decane hydrochloride; 2,7-Diazaspiro[4.5]decane-7-carboxylate hydrochloride; Boc-2,7-diazaspiro[4.5]decane HCl; 1,1-Dimethylethyl 2,7-diazaspiro[4.5]decane-7-carboxylate hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2,7-Diazaspiro[4.5]Decane-7-Carboxylic Acid, 1,1-Dimethylethyl Ester, (Hydrochloride)(1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.