Description

tert-Butyl 4-(6-Aminopyridin-3-Yl)-5,6-Dihydropyridine-1(2H)-Carboxylate is a high-value, multi-functional heterocyclic building block featuring both a protected amine and a Boc-protected dihydropyridine scaffold. This compound matters for its critical role in modern medicinal chemistry, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting neurological and cardiovascular diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those with fused heterocyclic systems.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Library Synthesis: A valuable building block for creating diverse compound libraries for high-throughput screening in drug discovery.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents with specific biological activity.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(6-Aminopyridin-3-Yl)-5,6-Dihydropyridine-1(2H)-Carboxylate
CAS No.	1279030-84-0
Molecular Formula	C15H21N3O2
Molecular Weight	275.35 g/mol
Synonyms	1-Boc-4-(6-Amino-3-pyridyl)-1,2,3,6-tetrahydropyridine; tert-Butyl 4-(6-amino-3-pyridinyl)-1,2,3,6-tetrahydropyridine-1-carboxylate; 4-(6-Aminopyridin-3-yl)-1,2,3,6-tetrahydropyridine-1-carboxylic acid tert-butyl ester; 1,2,3,6-Tetrahydropyridine-1-carboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester; 1-N-Boc-4-(6-aminopyridin-3-yl)-1,2,3,6-tetrahydropyridine; Boc-4-(6-Aminopyridin-3-yl)-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Aminopyridin-3-Yl)-5,6-Dihydropyridine-1(2H)-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and traceable to each production lot. We are committed to meeting the stringent requirements of pharmaceutical development and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.