Description

Rac Mono(Ethylhexyl) Phthalate-D4 is a deuterium-labeled isotopologue of a key phthalate ester derivative, serving as a critical internal standard for precise analytical quantification. This high-purity compound is essential for ensuring accuracy and reliability in sensitive mass spectrometry and chromatography-based analyses, where unlabeled compounds would cause interference. It is primarily required by analytical laboratories, environmental testing facilities, and research institutions engaged in method development, quality control, and trace-level detection studies of phthalates.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a deuterated internal standard in GC-MS and LC-MS/MS methods for the accurate quantification of phthalate esters, correcting for matrix effects and instrument variability.
• Environmental Analysis: Critical for tracing and quantifying phthalate contaminants in water, soil, and air samples to meet regulatory compliance and environmental monitoring standards.
• Food Safety & Packaging Testing: Employed in assays to detect phthalate migration from packaging materials into foodstuffs, supporting safety evaluations for regulatory bodies like the FDA and EFSA.
• Biomedical & Clinical Research: Facilitates the study of phthalate exposure and metabolism in biological matrices such as serum, urine, and tissue samples.
• Polymer & Material Science: Used in research to analyze plasticizer composition, degradation products, and leaching behavior from polyvinyl chloride (PVC) and other polymers.
• Pharmaceutical Impurity Profiling: Aids in the detection and quantification of potential genotoxic impurities (PGIs) or leachables from pharmaceutical packaging and delivery systems.
• Method Development & Validation: Serves as a key reagent for developing, optimizing, and validating new analytical protocols in compliance with ICH, ISO, or other guidelines.
• Forensic Toxicology: Applied in forensic analyses to determine exposure levels to specific phthalates in casework investigations.

Basic Information

Product Name	Rac Mono(Ethylhexyl) Phthalate-D4
CAS No.	1276197-22-8
Molecular Formula	C16H18D4O4
Molecular Weight	278.35 g/mol (approx.)
Synonyms	rac-Mono(2-ethylhexyl) Phthalate-d4; 1,2-Benzenedicarboxylic Acid, Mono(2-ethylhexyl) Ester-d4; MEHP-d4; Deuterated Mono(2-ethylhexyl) Phthalate; d4-MEHP; Phthalic Acid Mono(2-ethylhexyl) Ester-d4; rac-MEHP-d4; Isotopic Labeled MEHP
EINECS	Contact for details

Quality Control

Every batch of Rac Mono(Ethylhexyl) Phthalate-D4 is manufactured and controlled under a strict quality management system. The product undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity (≥98% D) and chemical purity (≥95% by HPLC). A comprehensive Certificate of Analysis (COA) detailing batch-specific results for identity, assay, and purity is provided with each shipment to ensure traceability and compliance with your research or quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry, and well-ventilated place. Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by GC)	≥ 90%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.