Description

1-(2-Fluoro-4-(Trifluoromethyl)Phenyl)Cyclopropanecarboxylic Acid is a high-value fluorinated cyclopropane derivative, a key building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and a trifluoromethyl group on the aromatic ring, makes it indispensable for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the fluorine motifs enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced materials with specific surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes.
• Fluorine Chemistry Building Block: A versatile synthon for introducing complex fluorinated aromatic systems into larger molecular architectures.
• Life Science Reagents: Used in the preparation of biochemical probes and diagnostic agents.

Basic Information

Product Name	1-(2-Fluoro-4-(Trifluoromethyl)Phenyl)Cyclopropanecarboxylic Acid
CAS No.	1274902-10-1
Molecular Formula	C11H8F4O2
Molecular Weight	248.17 g/mol
Synonyms	2-Fluoro-α-(trifluoromethyl)benzenepropanoic acid, α-cyclopropylidene; 1-[2-Fluoro-4-(trifluoromethyl)phenyl]cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-[2-fluoro-4-(trifluoromethyl)phenyl]-; 1-(2-Fluoro-4-trifluoromethylphenyl)cyclopropanecarboxylic acid; 2-Fluoro-4-(trifluoromethyl)phenyl cyclopropanecarboxylate (precursor form); F-TFM-PCPA (abbrev.); FTCPCA
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluoro-4-(Trifluoromethyl)Phenyl)Cyclopropanecarboxylic Acid adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.