Description

1-(9-Fluorenylmethyloxycarbonyl-Amino)-4,9-Dioxa-12-Dodecanamine Hydrochloride is a specialized, high-purity chemical building block designed for advanced synthesis. This compound matters for its role as a key intermediate in the production of complex molecules, offering a protected amine group and a hydrophilic linker for precise chemical assembly. It is primarily needed by research institutions and pharmaceutical companies engaged in peptide synthesis, bioconjugation, and the development of novel drug delivery systems. Our global supply ensures consistent quality and reliable availability for critical R&D and manufacturing processes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a crucial Fmoc-protected linker or spacer molecule for constructing peptide chains with specific solubility properties.
• Bioconjugation Chemistry: Used to attach peptides, drugs, or imaging agents to polymers, nanoparticles, or other biomolecules via its amine functionality.
• Drug Delivery System Development: Acts as a functionalized building block for creating targeted prodrugs or smart carrier systems with enhanced pharmacokinetics.
• Combinatorial Library Synthesis: A valuable reagent for generating diverse libraries of compounds in medicinal chemistry and high-throughput screening programs.
• Proteomics Research: Employed in the synthesis of affinity tags, cross-linking agents, or specialized probes for protein analysis and interaction studies.
• Material Science Functionalization: Used to introduce amine-reactive sites onto surfaces or materials for subsequent bio-functionalization.

Basic Information

Product Name	1-(9-Fluorenylmethyloxycarbonyl-Amino)-4,9-Dioxa-12-Dodecanamine Hydrochloride
CAS No.	1274891-99-4
Molecular Formula	C28H39N2O5Cl
Molecular Weight	519.07 g/mol
Synonyms	Fmoc-N-amido-PEG3-amine hydrochloride; 1-(Fmoc-amino)-4,9-dioxa-12-dodecanamine hydrochloride; 12-Amino-4,9-dioxa-1-dodecanamine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, hydrochloride; Fmoc-NH-PEG3-NH2·HCl; Nα-Fmoc-3,6,9-trioxa-1,12-dodecanediamine hydrochloride; Fmoc-12-amino-4,9-dioxadodecylamine hydrochloride; Fmoc-PEG3-amine hydrochloride; Fmoc-N-amido-triethyleneglycol-amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 1-(9-Fluorenylmethyloxycarbonyl-Amino)-4,9-Dioxa-12-Dodecanamine Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality protocols are designed to support compliance with cGMP and other relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.