Description

5-Oxa-2,6-Diaza-Spiro[3.4]Oct-6-Ene-2,7-Dicarboxylic Acid 2-tert-Butyl Ester is a high-value, multifunctional spirocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research, serving as a key precursor for constructing complex molecular architectures with potential biological activity. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs) and other high-performance materials.

Application

• Pharmaceutical Intermediate: A versatile scaffold for the synthesis of novel drug candidates, particularly in protease inhibitor and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities.
• Peptidomimetic Synthesis: The spirocyclic and heterocyclic structure makes it an ideal component for creating conformationally constrained peptide analogs.
• Chemical Biology Probes: Employed in the development of tool compounds and molecular probes for target identification and validation.
• Agrochemical Development: Serves as a sophisticated intermediate in the research and development of new crop protection agents.
• Academic & Contract Research: Used in universities and CROs for methodological development in synthetic organic chemistry.

Basic Information

Product Name	5-Oxa-2,6-Diaza-Spiro[3.4]Oct-6-Ene-2,7-Dicarboxylic Acid 2-tert-Butyl Ester
CAS No.	1273576-64-9
Molecular Formula	C11H15N2O5
Molecular Weight	255.25 g/mol
Synonyms	2-(tert-Butyl) 7H-5-Oxa-2,6-diazaspiro[3.4]oct-6-ene-2,7-dicarboxylate; 2-tert-Butyl 5-oxa-2,6-diazaspiro[3.4]oct-6-ene-2,7-dicarboxylate; 5-Oxa-2,6-diazaspiro[3.4]oct-6-ene-2,7-dicarboxylic acid, 2-(1,1-dimethylethyl) ester; Spirocyclic Oxadiazine Ester; tert-Butyl 5-oxa-2,6-diazaspiro[3.4]oct-6-ene-2-carboxylate-7-carboxylate; CAS 1273576-64-9
EINECS	Contact for details

Quality Control

Our production of 5-Oxa-2,6-Diaza-Spiro[3.4]Oct-6-Ene-2,7-Dicarboxylic Acid 2-tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.