Description

Spiro[2.3]Hexane-5-Carboxylic Acid CAS NO 1273567-26-2 is a high-value, strained spirocyclic carboxylic acid building block. This compound is prized for its unique three-dimensional structure, which is instrumental in modulating the physicochemical properties and biological activity of advanced molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, including the synthesis of novel active pharmaceutical ingredients (APIs) and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where its spirocyclic core can contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers, ligands, or additives where a rigid, three-dimensional scaffold is required to impart specific material properties.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and tools for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including studies on ring strain and novel cyclization reactions.

Basic Information

Product Name	Spiro[2.3]Hexane-5-Carboxylic Acid
CAS No.	1273567-26-2
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	Spiro[2.3]hexane-5-carboxylic acid; 5-Carboxyspiro[2.3]hexane; 1-Oxaspiro[2.3]hexane-4-carboxylic acid; Spirohexane-5-carboxylic acid; 4-Carboxy-1-oxaspiro[2.3]hexane; 1-Oxaspiro[2.3]hexane-4-carboxylic acid; Bicyclo[3.1.0]hexane-6-carboxylic acid, 2-oxa- (related structure); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Spiro[2.3]Hexane-5-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.