Description

4-(7-Oxo-5,8-Diazaspiro[3.4]Oct-6-Yl)Benzonitrile is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics targeting a range of diseases. It is primarily sought after by pharmaceutical R&D departments, biotechnology firms, and fine chemical manufacturers engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other enzyme-targeting molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic and nitrile functional groups.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation therapeutics.
• Chemical Biology Probes: Utilized in the development of selective chemical probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	4-(7-Oxo-5,8-Diazaspiro[3.4]Oct-6-Yl)Benzonitrile
CAS No.	1272755-89-1
Molecular Formula	C13H12N4O
Molecular Weight	240.26 g/mol
Synonyms	4-(7-Oxo-5,8-diazaspiro[3.4]oct-6-yl)benzonitrile; Benzonitrile, 4-(7-oxo-5,8-diazaspiro[3.4]oct-6-yl)-; 1272755-89-1; 4-(7-Oxo-5,8-diazaspiro[3.4]octan-6-yl)benzonitrile; 6-(4-Cyanophenyl)-5,8-diazaspiro[3.4]octan-7-one
EINECS	Contact for details

Quality Control

Our production of 4-(7-Oxo-5,8-Diazaspiro[3.4]Oct-6-Yl)Benzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC, NMR, and MS. We operate under a cGMP-compliant mindset suitable for non-GMP pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.