Description

n-GlcNAc-Biotin is a high-purity biochemical reagent designed for advanced research and development applications. This compound is critical for studying glycosylation processes and protein interactions through biotin-streptavidin affinity systems. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, proteomics, and pharmaceutical development. The product is supplied with full traceability and quality documentation to ensure reliable and reproducible results.

Application

• Glycobiology Research: As a key substrate or probe for studying O-GlcNAcylation, a critical post-translational modification.
• Bioconjugation & Labeling: Used to biotinylate proteins, peptides, or other molecules for detection, purification, or immobilization via streptavidin/avidin binding.
• Enzyme Activity Assays: Serves as a substrate for enzymes like O-GlcNAc transferase (OGT) in high-throughput screening and kinetic studies.
• Diagnostic Reagent Development: Incorporated into assay platforms for the detection of specific glycosylation-related biomarkers.
• Chemical Biology Tool: Enables the study of metabolic pathways and the functional roles of O-GlcNAc in cellular processes.
• Pharmaceutical R&D: Used in drug discovery programs targeting metabolic disorders, cancer, and neurodegenerative diseases linked to glycosylation.

Basic Information

Item	Details
Product Name	n-GlcNAc-Biotin
CAS No.	1272755-69-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Acetylglucosamine-Biotin; Biotinylated GlcNAc; O-GlcNAc-Biotin; Biotin-GlcNAc; 2-(Biotinamido)ethyl 2-acetamido-2-deoxy-β-D-glucopyranoside; UDP-GlcNAc analog-biotin conjugate; Glycosylation research probe
EINECS	Contact for details

Quality Control

Our n-GlcNAc-Biotin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation by spectroscopic methods. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing batch-specific results for identity, purity, and impurities. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Water, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.