Description

6-Thia-2-Azaspiro[3.3]Heptane-2-Carboxylic Acid tert-Butyl Ester is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by R&D teams and process chemists in the pharmaceutical and biotechnology industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting neurological disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained spirocyclic geometry.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Enables the creation of specialized tools for studying enzyme function and protein-protein interactions.
• Custom Synthesis: Foundation for the contract manufacturing of complex, non-commercial compounds for client-specific R&D projects.

Basic Information

Product Name	6-Thia-2-Azaspiro[3.3]Heptane-2-Carboxylic Acid tert-Butyl Ester
CAS No.	1272412-70-0
Molecular Formula	C10H17NO2S
Molecular Weight	215.31 g/mol
Synonyms	tert-Butyl 6-thia-2-azaspiro[3.3]heptane-2-carboxylate; 2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-thia-, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-6-thia-2-azaspiro[3.3]heptane; 2-Boc-6-thia-2-azaspiro[3.3]heptane; 6-Thia-2-azaspiro[3.3]heptane-2-carboxylic acid 1,1-dimethylethyl ester; Spirocyclic Sulfur-Nitrogen Building Block
EINECS	Contact for details

Quality Control

Our 6-Thia-2-Azaspiro[3.3]Heptane-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide materials suitable for preclinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.