Description

2,9-Dioxa-6-Azaspiro[3,5]Nonane-6-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel drug candidates, offering a versatile building block for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for constructing novel heterocyclic and spirocyclic compounds in drug discovery programs.
• Protease Inhibitor Development: Its structural motifs are valuable in the research and development of protease inhibitor candidates.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis for clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2,9-Dioxa-6-Azaspiro[3,5]Nonane-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1272412-69-7
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	tert-Butyl 2,9-dioxa-6-azaspiro[3.5]nonane-6-carboxylate; 6-Boc-2,9-dioxa-6-azaspiro[3.5]nonane; 2,9-Dioxa-6-azaspiro[3.5]nonane-6-carboxylic acid, 1,1-dimethylethyl ester; 6-(tert-Butoxycarbonyl)-2,9-dioxa-6-azaspiro[3.5]nonane; Boc-Protected 2,9-Dioxa-6-Azaspiro[3.5]Nonane; Spirocyclic Boc-Amine Ester
EINECS	Contact for details

Quality Control

Our 2,9-Dioxa-6-Azaspiro[3,5]Nonane-6-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your research and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.