Description

1-Cyclobutylethane-1,2-Diamine is a specialized chiral diamine building block of significant interest in advanced organic synthesis. Its unique cyclobutyl backbone and bifunctional amine groups make it a valuable precursor for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst ligand development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands used in transition metal catalysis to achieve high enantioselectivity in synthetic reactions.
• Agrochemical Research: Used in the development of new herbicides and pesticides where specific stereochemistry is crucial for bioactivity.
• Polymer Modification: Employed as a cross-linking agent or chain extender in the production of specialty polyamides and polyurethanes with enhanced thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Fine Chemical Synthesis: A versatile building block for creating complex natural product analogs and other high-value fine chemicals.

Basic Information

Item	Details
Product Name	1-Cyclobutylethane-1,2-Diamine
CAS No.	1270470-80-8
Molecular Formula	C6H14N2
Molecular Weight	114.19 g/mol
Synonyms	(1R,2R)-1-Cyclobutylethane-1,2-diamine; (1R,2R)-1-Cyclobutyl-1,2-ethanediamine; (1R,2R)-2-Aminocyclobutylethylamine; (1R,2R)-1,2-Diamino-1-cyclobutylethane; trans-1-Cyclobutylethane-1,2-diamine; Chiral Cyclobutyl Diamine; 1-Cyclobutyl-1,2-ethylenediamine (stereoisomer)
EINECS	Contact for details

Quality Control

Our 1-Cyclobutylethane-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.