Description

3-Amino-3-(3-Bromo-5-Fluorophenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a halogenated aromatic side chain. This compound serves as a critical pharmaceutical intermediate and custom building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the synthesis of targeted therapeutics and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique halogenated phenylalanine-like structure.
• Peptidomimetic Synthesis: Incorporation into peptide analogs to enhance metabolic stability, binding affinity, and membrane permeability.
• Agrochemical Development: Serves as a precursor for creating novel herbicides, fungicides, or plant growth regulators with specific activity profiles.
• Chemical Biology Probes: Utilized in the development of enzyme inhibitors, receptor ligands, and other biochemical tools for target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring this specific halogenated amino acid scaffold.

Basic Information

Item	Detail
Product Name	3-Amino-3-(3-Bromo-5-Fluorophenyl)Propanoic Acid
CAS No.	1270470-53-5
Molecular Formula	C9H9BrFNO2
Molecular Weight	262.08 g/mol
Synonyms	β-Amino-3-bromo-5-fluorohydrocinnamic Acid; 3-Amino-3-(3-bromo-5-fluorophenyl)propionic Acid; (3-Bromo-5-fluorophenyl)-β-alanine; 3-(3-Bromo-5-fluorophenyl)-β-alanine; 3-(3-Bromo-5-fluorophenyl)-3-aminopropanoic Acid; DL-3-Amino-3-(3-bromo-5-fluorophenyl)propanoic Acid; 3-Bromo-5-fluoro-DL-phenylalanine homolog
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(3-Bromo-5-Fluorophenyl)Propanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and KF for moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP guidelines for early-phase development. Specifications are tailored to meet the rigorous demands of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.