Description

(1S)-1-(4-Bromophenyl)-2-Methoxyethan-1-Amine CAS NO 1270099-77-8 is a chiral amine building block featuring a bromophenyl group and a methoxyethyl side chain. This compound is a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and advanced organic materials, where its specific stereochemistry and functional groups enable precise molecular construction. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the bromophenyl moiety is a common structural motif.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring a specific enantiomer with a bromine handle for further functionalization.

Basic Information

Product Name	(1S)-1-(4-Bromophenyl)-2-Methoxyethan-1-Amine
CAS No.	1270099-77-8
Molecular Formula	C9H12BrNO
Molecular Weight	230.10 g/mol
Synonyms	(S)-1-(4-Bromophenyl)-2-methoxyethanamine; (1S)-1-(4-Bromophenyl)-2-methoxyethanamine; (S)-1-(p-Bromophenyl)-2-methoxyethylamine; (S)-α-(4-Bromophenyl)-β-methoxyethylamine; (S)-2-Methoxy-1-(4-bromophenyl)ethylamine; (S)-4'-Bromo-2-methoxyphenethylamine; p-Bromo-(S)-methoxyphenethylamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. For this chiral amine, quality is assured through comprehensive analytical methods including chiral HPLC to confirm enantiomeric excess (ee) and standard purity assays. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available upon request. We adhere to cGMP guidelines for the production of materials intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.