Description

(S)-2-Amino-2-(2-Fluorophenyl)Ethanol Hydrochloride CAS NO 1269773-22-9 is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel fluorinated compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Chiral Building Block: Used in asymmetric synthesis to construct complex molecules with high enantiomeric purity for medicinal chemistry and process development.
• Agrochemical Research: Serves as a precursor in the development of new fluorinated pesticides and herbicides, leveraging the fluorine atom's ability to modulate biological activity and stability.
• Chemical Biology & Proteomics: Employed as a specialty reagent for labeling and modifying biomolecules in research applications.
• Catalyst & Ligand Development: Acts as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(S)-2-Amino-2-(2-Fluorophenyl)Ethanol Hydrochloride
CAS No.	1269773-22-9
Molecular Formula	C8H11ClFNO
Molecular Weight	191.63 g/mol
Synonyms	(S)-2-Amino-2-(2-fluorophenyl)ethanol HCl; (1S)-2-Amino-1-(2-fluorophenyl)ethanol hydrochloride; (S)-2-Fluorophenylethanolamine hydrochloride; (S)-2-Amino-1-(2-fluorophenyl)ethan-1-ol hydrochloride; (S)-2-Fluoro-β-amino-phenethyl alcohol hydrochloride; (S)-1-(2-Fluorophenyl)-2-aminoethanol hydrochloride; (S)-2-(2-Fluorophenyl)-2-hydroxyethylamine hydrochloride; (S)-Norfenefrine fluoro analog hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-2-(2-Fluorophenyl)Ethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity (typically ≥98.0% by HPLC), enantiomeric excess (typically ≥99.0% ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.