Description

(S)-3-Methyl-1-Phenylbutan-1-Amine-Hcl CAS NO 1269470-38-3 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry and high chemical purity make it an essential intermediate for producing enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective synthesis to control the configuration of new stereocenters.
• Agrochemical Research: Intermediate in the synthesis of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in homogeneous catalysis (e.g., for hydrogenation or cross-coupling reactions).
• Fine Chemical Production: Building block for advanced materials, specialty polymers, and complex fragrance or flavor molecules requiring specific stereochemistry.
• Academic & Contract Research: Vital reagent for methodological development in organic chemistry and medicinal chemistry research within universities and CROs (Contract Research Organizations).

Basic Information

Product Name	(S)-3-Methyl-1-Phenylbutan-1-Amine Hydrochloride
CAS No.	1269470-38-3
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol
Synonyms	(S)-3-Methyl-1-phenylbutan-1-amine hydrochloride; (S)-1-Phenyl-3-methylbutylamine hydrochloride; (S)-3-Methyl-1-phenylbutylamine HCl; (S)-Phenylisobutylamine hydrochloride; (S)-Homoisoamylamine hydrochloride; (S)-1-Amino-3-methyl-1-phenylbutane hydrochloride; (S)-AMPB HCl; (S)-Fenbutrazine impurity standard
EINECS	Contact for details

Quality Control

Our (S)-3-Methyl-1-Phenylbutan-1-Amine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.