Description

2-(2-Fluorophenyl)Cyclopropan-1-Amine Hydrochloride is a high-purity, synthetically valuable organic building block and pharmaceutical intermediate. Its unique cyclopropylamine structure, functionalized with a fluorinated aromatic ring, makes it a critical precursor for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate fluorinated cyclopropane motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore the effects of fluorination and the rigid cyclopropane scaffold on bioactivity and metabolic stability.
• Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.

Basic Information

Product Name	2-(2-Fluorophenyl)Cyclopropan-1-Amine Hydrochloride
CAS No.	1269152-01-3
Molecular Formula	C9H11ClFN
Molecular Weight	187.64 g/mol
Synonyms	1-Cyclopropanamine, 2-(2-fluorophenyl)-, hydrochloride; 2-(2-Fluorophenyl)cyclopropanamine hydrochloride; (1R,2S)-2-(2-Fluorophenyl)cyclopropan-1-amine hydrochloride (for chiral form); (1S,2R)-2-(2-Fluorophenyl)cyclopropan-1-amine hydrochloride; 2-(o-Fluorophenyl)cyclopropylamine HCl; trans-2-(2-Fluorophenyl)cyclopropanamine hydrochloride; 2-Fluorophenylcyclopropylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)Cyclopropan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original packaging to prevent degradation upon prolonged exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.